Dr Peter Georgeson
I am a postdoctoral cancer researcher based at The University of Melbourne in Associate Professor Dan Buchanan's Colorectal Oncogenomics Group.
I have an ongoing interest in cancer genomics, statistical methods, and machine learning. My current research focuses on the application of tumour mutational signatures to understanding and detecting the underlying aetiology driving different sub-types of colorectal cancer.
Research Interests: mutational signatures, colorectal cancer, statistical learning, genomics, bioinformatics.
✉️ peter.georgeson AT unimelb.edu.au
Publications
Waist circumference, a body shape index, and molecular subtypes of colorectal cancer: A pooled analysis of four cohort studies. Chalitsios, Christos V.; Markozannes, Georgios; Papagiannopoulos, Christos; Aglago, Elom K.; Berndt, Sonja I.; Buchanan, Daniel D.; Campbell, Peter T.; Cao, Yin; Chan, Andrew T.; Dimou, Niki; Drew, David A.; French, Amy J.; Georgeson, Peter; Giannakis, Marios; Gruber, Stephen B.; Gunter, Marc J.; Harrison, Tabitha A.; Hoffmeister, Michael; Hsu, Li; Huang, Wen-Yi; Hullar, Meredith AJ.; Huyghe, Jeroen R.; Lynch, Brigid M.; Moreno, Victor; Newton, Christina C.; Nowak, Jonathan A.; Obón-Santacana, Mireia; Ogino, Shuji; Qu, Conghui; Schmit, Stephanie L.; Steinfelder, Robert S.; Sun, Wei; Thomas, Claire E.; Toland, Amanda E.; Trinh, Quang M.; Ugai, Tomotaka; Um, Caroline Y.; Van Guelpen, Bethany; Zaidi, Syed H.; Murphy, Neil; Peters, Ulrike; Phipps, Amanda I.; Tsilidis, Konstantinos K.Cancer Epidemiology, Biomarkers & Prevention. 2025.
Adenomas from individuals with pathogenic biallelic variants in the MUTYH and NTHL1 genes demonstrate base excision repair tumour mutational signature profiles similar to colorectal cancers, expanding potential diagnostic and variant classification applications. Walker, Romy; Joo, Jihoon E.; Mahmood, Khalid; Clendenning, Mark; Como, Julia; Preston, Susan G.; Joseland, Sharelle; Pope, Bernard J.; Medeiros, Ana B.D.; Murillo, Brenely V.; Pachter, Nicholas; Sweet, Kevin; Spigelman, Allan D.; Groves, Alexandra; Gleeson, Margaret; Bernatowicz, Krzysztof; Poplawski, Nicola; Andrews, Lesley; Healey, Emma; Gallinger, Steven; Grant, Robert C.; Win, Aung K.; Hopper, John L.; Jenkins, Mark A.; Torrezan, Giovana T.; Rosty, Christophe; Macrae, Finlay A.; Winship, Ingrid M.; Buchanan, Daniel D.; Georgeson, PeterTranslational Oncology. 2025.
DNA Mismatch Repair Gene Mosaicism Is Rare in People With Mismatch Repair-Deficient Cancers. Walker, Romy; Joo, Jihoon E.; Mahmood, Khalid; Georgeson, Peter; Clendenning, Mark; Joseland, Sharelle; Como, Julia; Preston, Susan G.; Stoss, Sarah; Rosty, Christophe; Pope, Bernard J.; Macrae, Finlay A.; Win, Aung K.; Hopper, John L.; Jenkins, Mark A.; Potter, John D.; Samadder, N. Jewel; Walsh, Michael D.; Winship, Ingrid M.; Buchanan, Daniel D.Gastroenterology. 2025.
Folate intake and colorectal cancer risk according to genetic subtypes defined by targeted tumor sequencing. Aglago, Elom K; Qu, Conghui; Harlid, Sophia; Phipps, Amanda I; Steinfelder, Robert S; Ogino, Shuji; Thomas, Claire E; Hsu, Li; Toland, Amanda E; Brenner, Hermann; Berndt, Sonja I; Buchanan, Daniel D; Campbell, Peter T; Cao, Yin; Chan, Andrew T; Drew, David A; Figueiredo, Jane C; French, Amy J; Gallinger, Steven; Georgeson, Peter; Giannakis, Marios; Goode, Ellen L; Gruber, Stephen B; Gunter, Marc J; Harrison, Tabitha A; Hoffmeister, Michael; Huang, Wen-Yi; Hullar, Meredith AJ; Huyghe, Jeroen R; Jenkins, Mark A; Lynch, Brigid M; Moreno, Victor; Murphy, Neil; Newton, Christina C; Nowak, Jonathan A; Obón-Santacana, Mireia; Sun, Wei; Ugai, Tomotaka; Um, Caroline Y; Zaidi, Syed H; Tsilidis, Konstantinos K; van Guelpen, Bethany; Peters, UlrikeThe American Journal of Clinical Nutrition. 2024.
Epidemiologic Factors in Relation to Colorectal Cancer Risk and Survival by Genotoxic Colibactin Mutational Signature. Thomas, Claire E.; Georgeson, Peter; Qu, Conghui; Steinfelder, Robert S.; Buchanan, Daniel D.; Song, Mingyang; Harrison, Tabitha A.; Um, Caroline Y.; Hullar, Meredith A.; Jenkins, Mark A.; Van Guelpen, Bethany; Lynch, Brigid M.; Melaku, Yohannes Adama; Huyghe, Jeroen R.; Aglago, Elom K.; Berndt, Sonja I.; Boardman, Lisa A.; Campbell, Peter T.; Cao, Yin; Chan, Andrew T.; Drew, David A.; Figueiredo, Jane C.; French, Amy J.; Giannakis, Marios; Goode, Ellen L.; Gruber, Stephen B.; Gsur, Andrea; Gunter, Marc J.; Hoffmeister, Michael; Hsu, Li; Huang, Wen-Yi; Moreno, Victor; Murphy, Neil; Newcomb, Polly A.; Newton, Christina C.; Nowak, Jonathan A.; Obón-Santacana, Mireia; Ogino, Shuji; Sun, Wei; Toland, Amanda E.; Trinh, Quang M.; Ugai, Tomotaka; Zaidi, Syed H.; Peters, Ulrike; Phipps, Amanda I.Cancer Epidemiology, Biomarkers & Prevention. 2024.
Intratumoral presence of the genotoxic gut bacteria pks+ E. coli, Enterotoxigenic Bacteroides fragilis, and Fusobacterium nucleatum and their association with clinicopathological and molecular features of colorectal cancer. Joo, Jihoon E.; Chu, Yen Lin; Georgeson, Peter; Walker, Romy; Mahmood, Khalid; Clendenning, Mark; Meyers, Aaron L.; Como, Julia; Joseland, Sharelle; Preston, Susan G.; Diepenhorst, Natalie; Toner, Julie; Ingle, Danielle J.; Sherry, Norelle L.; Metz, Andrew; Lynch, Brigid M.; Milne, Roger L.; Southey, Melissa C.; Hopper, John L.; Win, Aung Ko; Macrae, Finlay A.; Winship, Ingrid M.; Rosty, Christophe; Jenkins, Mark A.; Buchanan, Daniel D.British Journal of Cancer. 2024.
Inherited BRCA1 and RNF43 pathogenic variants in a familial colorectal cancer type X family. Chan, James M.; Clendenning, Mark; Joseland, Sharelle; Georgeson, Peter; Mahmood, Khalid; Joo, Jihoon E.; Walker, Romy; Como, Julia; Preston, Susan; Chai, Shuyi Marci; Chu, Yen Lin; Meyers, Aaron L.; Pope, Bernard J.; Duggan, David; Fink, J. Lynn; Macrae, Finlay A.; Rosty, Christophe; Winship, Ingrid M.; Jenkins, Mark A.; Buchanan, Daniel D.Familial Cancer. 2023.
DNA mismatch repair gene variant classification: evaluating the utility of somatic mutations and mismatch repair deficient colonic crypts and endometrial glands. Walker, Romy; Mahmood, Khalid; Como, Julia; Clendenning, Mark; Joo, Jihoon E.; Georgeson, Peter; Joseland, Sharelle; Preston, Susan G.; Pope, Bernard J.; Chan, James M.; Austin, Rachel; Bojadzieva, Jasmina; Campbell, Ainsley; Edwards, Emma; Gleeson, Margaret; Goodwin, Annabel; Harris, Marion T.; Ip, Emilia; Kirk, Judy; Mansour, Julia; Marfan, Helen; Nichols, Cassandra; Pachter, Nicholas; Ragunathan, Abiramy; Spigelman, Allan; Susman, Rachel; Christie, Michael; Jenkins, Mark A.; Pai, Rish K.; Rosty, Christophe; Macrae, Finlay A.; Winship, Ingrid M.; Buchanan, Daniel D.. 2023.
Genotoxic colibactin mutational signature in colorectal cancer is associated with clinicopathological features, specific genomic alterations and better survival. Georgeson, Peter; Steinfelder, Robert S.; Harrison, Tabitha A.; Pope, Bernard J.; Zaidi, Syed H.; Qu, Conghui; Lin, Yi; Joo, Jihoon E.; Mahmood, Khalid; Clendenning, Mark; Walker, Romy; Aglago, Elom K; Berndt, Sonja I.; Brenner, Hermann; Campbell, Peter T.; Cao, Yin; Chan, Andrew T.; Chang-Claude, Jenny; Dimou, Niki; Doheny, Kimberly F.; Drew, David A.; Figueiredo, Jane C.; French, Amy J.; Gallinger, Steven; Giannakis, Marios; Giles, Graham G.; Goode, Ellen L; Gruber, Stephen B; Gsur, Andrea; Gunter, Marc J.; Harlid, Sophia; Hoffmeister, Michael; Hsu, Li; Huang, Wen-Yi; Huyghe, Jeroen R; Manson, JoAnn E.; Moreno, Victor; Murphy, Neil; Nassir, Rami; Newton, Christina C.; Nowak, Jonathan A.; Obón-Santacana, Mireia; Ogino, Shuji; Pai, Rish K.; Papadimitrou, Nikos; Potter, John D.; Schoen, Robert E.; Song, Mingyang; Sun, Wei; Toland, Amanda E.; Trinh, Quang M.; Tsilidis, Kostas; Ugai, Tomotaka; Um, Caroline Y; Macrae, Finlay A.; Rosty, Christophe; Hudson, Thomas J.; Winship, Ingrid M.; Phipps, Amanda I.; Jenkins, Mark A.; Peters, Ulrike; Buchanan, Daniel D.. 2023.
A tumor focused approach to resolving the etiology of DNA mismatch repair deficient tumors classified as suspected Lynch syndrome. Walker, Romy; Mahmood, Khalid; Joo, Jihoon E.; Clendenning, Mark; Georgeson, Peter; Como, Julia; Joseland, Sharelle; Preston, Susan G.; Antill, Yoland; Austin, Rachel; Boussioutas, Alex; Bowman, Michelle; Burke, Jo; Campbell, Ainsley; Daneshvar, Simin; Edwards, Emma; Gleeson, Margaret; Goodwin, Annabel; Harris, Marion T.; Henderson, Alex; Higgins, Megan; Hopper, John L.; Hutchinson, Ryan A.; Ip, Emilia; Isbister, Joanne; Kasem, Kais; Marfan, Helen; Milnes, Di; Ng, Annabelle; Nichols, Cassandra; O’Connell, Shona; Pachter, Nicholas; Pope, Bernard J.; Poplawski, Nicola; Ragunathan, Abiramy; Smyth, Courtney; Spigelman, Allan; Storey, Kirsty; Susman, Rachel; Taylor, Jessica A.; Warwick, Linda; Wilding, Mathilda; Williams, Rachel; Win, Aung K.; Walsh, Michael D.; Macrae, Finlay A.; Jenkins, Mark A.; Rosty, Christophe; Winship, Ingrid M.; Buchanan, Daniel D.. 2023.
Evaluating Multiple Next-Generation Sequencing–Derived Tumor Features to Accurately Predict DNA Mismatch Repair Status. Walker, Romy; Georgeson, Peter; Mahmood, Khalid; Joo, Jihoon E.; Makalic, Enes; Clendenning, Mark; Como, Julia; Preston, Susan; Joseland, Sharelle; Pope, Bernard J.; Hutchinson, Ryan A.; Kasem, Kais; Walsh, Michael D.; Macrae, Finlay A.; Win, Aung K.; Hopper, John L.; Mouradov, Dmitri; Gibbs, Peter; Sieber, Oliver M.; O’Sullivan, Dylan E.; Brenner, Darren R.; Gallinger, Steven; Jenkins, Mark A.; Rosty, Christophe; Winship, Ingrid M.; Buchanan, Daniel D.The Journal of Molecular Diagnostics. 2023.
Evaluating multiple next-generation sequencing derived tumor features to accurately predict DNA mismatch repair status. Walker, Romy; Georgeson, Peter; Mahmood, Khalid; Joo, Jihoon E.; Makalic, Enes; Clendenning, Mark; Como, Julia; Preston, Susan; Joseland, Sharelle; Pope, Bernard J.; Hutchinson, Ryan; Kasem, Kais; Walsh, Michael D.; Macrae, Finlay A.; Win, Aung K.; Hopper, John L.; Mouradov, Dmitri; Gibbs, Peter; Sieber, Oliver M.; O’Sullivan, Dylan E.; Brenner, Darren R.; Gallinger, Steven; Jenkins, Mark A.; Rosty, Christophe; Winship, Ingrid M.; Buchanan, Daniel D.. 2022.
Long-read assembly and comparative evidence-based reanalysis of Cryptosporidium genome sequences reveal expanded transporter repertoire and duplication of entire chromosome ends including subtelomeric regions. Rodrigo P. Baptista; Yiran Li; Adam Sateriale; Mandy J. Sanders; Karen L. Brooks; Alan Tracey; Brendan R.E. Ansell; Aaron R. Jex; Garrett W. Cooper; Ethan D. Smith; Rui Xiao; Jennifer E. Dumaine; Peter Georgeson; Bernard J. Pope; Matthew Berriman; Boris Striepen; James A. Cotton; Jessica C. KissingerGenome Research. 2021.
MSH2-deficient prostate tumours have a distinct immune response and clinical outcome compared to MSH2-deficient colorectal or endometrial cancer. McCoy, Patrick; Mangiola, Stefano; Macintyre, Geoff; Hutchinson, Ryan; Tran, Ben; Pope, Bernard; Georgeson, Peter; Hong, Matthew K. H.; Kurganovs, Natalie; Lunke, Sebastian; Clarkson, Michael J.; Cmero, Marek; Kerger, Michael; Stuchbery, Ryan; Chow, Ken; Haviv, Izhak; Ryan, Andrew; Costello, Anthony J.; Corcoran, Niall M.; Hovens, Christopher M.Prostate Cancer and Prostatic Diseases. 2021.
Rare germline variants in the AXIN2 gene in families with colonic polyposis and colorectal cancer. James M. Chan; Mark Clendenning; Sharelle Joseland; Peter Georgeson; Khalid Mahmood; Romy Walker; Julia Como; Jihoon E. Joo; Susan Preston; Ryan A. Hutchinson; Bernard J. Pope; Andrew Metz; Catherine Beard; Rebecca Purvis; Julie Arnold; Varnika Vijay; Galina Konycheva; Nathan Atkinson; Susan Parry; Mark A. Jenkins; Finlay A. Macrae; Christophe Rosty; Ingrid M. Winship; Daniel D. BuchananFamilial Cancer. 2021.
Evaluating the utility of tumour mutational signatures for identifying hereditary colorectal cancer and polyposis syndrome carriers. Peter Georgeson; Bernard J Pope; Christophe Rosty; Mark Clendenning; Khalid Mahmood; Jihoon E Joo; Romy Walker; Ryan A Hutchinson; Susan Preston; Julia Como; Sharelle Joseland; Aung Ko Win; Finlay A Macrae; John L Hopper; Dmitri Mouradov; Peter Gibbs; Oliver M Sieber; Dylan E O'Sullivan; Darren R Brenner; Steve Gallinger; Mark A Jenkins; Ingrid M Winship; Daniel D BuchananGut. 2021.
DNA Methylation Signatures and the Contribution of Age-Associated Methylomic Drift to Carcinogenesis in Early-Onset Colorectal Cancer. Joo, Jihoon E.; Clendenning, Mark; Wong, Ee Ming; Rosty, Christophe; Mahmood, Khalid; Georgeson, Peter; Winship, Ingrid M.; Preston, Susan G.; Win, Aung Ko; Dugué, Pierre-Antoine; Jayasekara, Harindra; English, Dallas; Macrae, Finlay A.; Hopper, John L.; Jenkins, Mark A.; Milne, Roger L.; Giles, Graham G.; Southey, Melissa C.; Buchanan, Daniel D.Cancers. 2021.
Germline and Tumor Sequencing as a Diagnostic Tool To Resolve Suspected Lynch Syndrome. Bernard J. Pope; Mark Clendenning; Christophe Rosty; Khalid Mahmood; Peter Georgeson; Jihoon E. Joo; Romy Walker; Ryan A. Hutchinson; Harindra Jayasekara; Sharelle Joseland; Julia Como; Susan Preston; Amanda B. Spurdle; Finlay A. Macrae; Aung K. Win; John L. Hopper; Mark A. Jenkins; Ingrid M. Winship; Daniel D. BuchananThe Journal of Molecular Diagnostics. 2021.
Bionitio: demonstrating and facilitating best practices for bioinformatics command-line software. Georgeson, Peter; Syme, Anna; Sloggett, Clare; Chung, Jessica; Dashnow, Harriet; Milton, Michael; Lonsdale, Andrew; Powell, David; Seemann, Torsten; Pope, BernardGigaScience. 2019.
Tumor mutational signatures in sebaceous skin lesions from individuals with Lynch syndrome. Georgeson, Peter; Walsh, Michael D.; Clendenning, Mark; Daneshvar, Simin; Pope, Bernard J.; Mahmood, Khalid; Joo, Jihoon E.; Jayasekara, Harindra; Jenkins, Mark A.; Winship, Ingrid M.; Buchanan, Daniel D.Molecular Genetics & Genomic Medicine. 2019.
Annotation of the Giardia proteome through structure-based homology and machine learning. Ansell, Brendan R E; Pope, Bernard J; Georgeson, Peter; Emery-Corbin, Samantha J; Jex, Aaron RGigaScience. 2018.
sEst: Accurate Sex-Estimation and Abnormality Detection in Methylation Microarray Data. Jung, Chol-Hee; Park, Daniel J.; Georgeson, Peter; Mahmood, Khalid; Milne, Roger L.; Southey, Melissa C.; Pope, Bernard J.International Journal of Molecular Sciences. 2018.
Variant effect prediction tools assessed using independent, functional assay-based datasets: implications for discovery and diagnostics. Mahmood, Khalid; Jung, Chol-hee; Philip, Gayle; Georgeson, Peter; Chung, Jessica; Pope, Bernard J.; Park, Daniel J.Human Genomics. 2017.
Diagnostic Impact and Cost-effectiveness of Whole-Exome Sequencing for Ambulant Children With Suspected Monogenic Conditions. Tan, Tiong Yang; Dillon, Oliver James; Stark, Zornitza; Schofield, Deborah; Alam, Khurshid; Shrestha, Rupendra; Chong, Belinda; Phelan, Dean; Brett, Gemma R.; Creed, Emma; Jarmolowicz, Anna; Yap, Patrick; Walsh, Maie; Downie, Lilian; Amor, David J.; Savarirayan, Ravi; McGillivray, George; Yeung, Alison; Peters, Heidi; Robertson, Susan J.; Robinson, Aaron J.; Macciocca, Ivan; Sadedin, Simon; Bell, Katrina; Oshlack, Alicia; Georgeson, Peter; Thorne, Natalie; Gaff, Clara; White, Susan M.JAMA Pediatrics. 2017.
An Emerging Female Phenotype with Loss‐of‐Function Mutations in the Aristaless‐ Related Homeodomain Transcription Factor ARX. Mattiske, Tessa; Moey, Ching; Vissers, Lisenka E.; Thorne, Natalie; Georgeson, Peter; Bakshi, Madhura; Shoubridge, CherylHuman Mutation. 2017.
Diagnostic and cost utility of whole exome sequencing in peripheral neuropathy. Walsh, Maie; Bell, Katrina M.; Chong, Belinda; Creed, Emma; Brett, Gemma R.; Pope, Kate; Thorne, Natalie P.; Sadedin, Simon; Georgeson, Peter; Phelan, Dean G.; Day, Timothy; Taylor, Jessica A.; Sexton, Adrienne; Lockhart, Paul J.; Kiers, Lynette; Fahey, Michael; Macciocca, Ivan; Gaff, Clara L.; Oshlack, Alicia; Yiu, Eppie M.; James, Paul A.; Stark, Zornitza; Ryan, Monique M.Annals of Clinical and Translational Neurology. 2017.
Single nucleotide-level mapping of DNA double-strand breaks in human HEK293T cells. Bernard J. Pope; Khalid Mahmood; Chol-hee Jung; Peter Georgeson; Daniel J. ParkGenomics Data. 2017.
UNDR ROVER - a fast and accurate variant caller for targeted DNA sequencing. Park, Daniel J.; Li, Roger; Lau, Edmund; Georgeson, Peter; Nguyen-Dumont, Tú; Pope, Bernard J.BMC Bioinformatics. 2016.
A prospective evaluation of whole-exome sequencing as a first-tier molecular test in infants with suspected monogenic disorders. Stark, Zornitza; Tan, Tiong Y.; Chong, Belinda; Brett, Gemma R.; Yap, Patrick; Walsh, Maie; Yeung, Alison; Peters, Heidi; Mordaunt, Dylan; Cowie, Shannon; Amor, David J.; Savarirayan, Ravi; McGillivray, George; Downie, Lilian; Ekert, Paul G.; Theda, Christiane; James, Paul A.; Yaplito-Lee, Joy; Ryan, Monique M.; Leventer, Richard J.; Creed, Emma; Macciocca, Ivan; Bell, Katrina M.; Oshlack, Alicia; Sadedin, Simon; Georgeson, Peter; Anderson, Charlotte; Thorne, Natalie; Gaff, Clara; White, Susan M.Genetics in Medicine. 2016.
Presentations
- Novel insights from the investigation of experimental mutational signatures in early-onset colorectal cancer and colonic polyps
AACR Special Conference in Cancer Research: The Rise in Early Onset Cancers – Knowledge Gaps and Research Opportunities (Montreal, Canada) (December, 2025). Poster presentation. - Characterizing the clinicopathological, genomic and spatial transcriptomic features of colibactin-induced colorectal cancers
AACR Special Conference in Cancer Research: The Rise in Early Onset Cancers – Knowledge Gaps and Research Opportunities (Montreal, Canada) (December, 2025). Poster presentation. - Somatic Mutational Signatures in Premalignant Colorectal Polyps Reveal Inherited Syndromes and Unexplained Aetiologies
Familial Aspects of Cancer Research and Practice (Kingscliff, Australia) (August, 2025). Accepted oral presentation. - Tumour mutational signatures for diagnosis and variant classification of hereditary colorectal cancer syndromes
Royal Melbourne Hospital Medical Grand Rounds (Melbourne, Australia) (April, 2025). Invited speaker. - Using tumour mutational signatures for diagnosing and variant classification of hereditary colorectal cancer syndromes
Colon Cancer Family Registry Cohort - Scientific Symposium (Hawaii, USA) (October, 2024). Invited speaker. - Improving hereditary colorectal cancer classification through mutational signature profiling
Human Genetics Society of Australasia (September, 2024). Invited speaker. - Improving hereditary CRC gene variant classification through tumour profiling
Familial Aspects of Cancer Research and Practice (Kingscliff, Australia) (August, 2024). Invited speaker. - Evidence of the accuracy of the KRAS c.34G>T p.G12C somatic mutation as a biomarker of germline biallelic MUTYH pathogenic variant carrier status
Familial Aspects of Cancer Research and Practice (Kingscliff, Australia) (August, 2024). Accepted oral presentation. - The exome-wide genomic profile of Lynch syndrome-related colorectal cancers differs by affected gene: implications for determining pathways of tumourigenesis
International Society for Gastrointestinal Hereditary Tumours (Barcelona, Spain) (June, 2024). Accepted oral presentation. - Genomic profiling of non-cancerous bowel tumours to improve prediction of progression to bowel cancer
Cure Cancer Lunch and Learn Series (2024). Public Seminar. - Genomic profiling of non-cancerous bowel tumours to improve prediction of progression to bowel cancer
Cure Cancer Research Symposium (2024). Invited oral presentation. - Genomic profiling of colorectal adenomas to identify inherited colorectal cancer and polyposis syndrome carriers
Familial Aspects of Cancer Research and Practice (Kingscliff, Australia) (2023). Accepted oral presentation. - Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures
International Society for Gastrointestinal Hereditary Tumours (New Jersey, USA) (2022). Accepted oral presentation. - The utility of base-excision repair tumor mutational signatures for identifying biallelic MUTYH carriers and classifying germline variants of uncertain clinical significance using colorectal cancer panel-sequenced genomic data
European Hereditary Tumour Group (EHTG) (2021). Accepted oral presentation. - Evaluating the clinical applicability of tumour mutational signatures in colorectal cancer
University of Melbourne Cancer Center Research (UMCCR) (2021). Seminar. - The utility of base-excision repair tumor mutational signatures for identifying biallelic MUTYH carriers and classifying germline variants of uncertain clinical significance using colorectal cancer panel-sequenced genomic data
Familial Aspects of Cancer Research and Practice (Kingscliff, Australia) (2021). Accepted oral presentation. - Identifying MUTYH-associated polyposis using panel-sequenced genomic data
The Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO) Tumour Working Group (2020). Oral presentation. - Evaluating tumour mutational signatures for classification of mismatch repair deficiency and identification of Lynch Syndrome and MLH1 methylated subtypes
International Society for Gastrointestinal Hereditary Tumours (Auckland, New Zealand) (2019). Accepted oral presentation. - The Clinical Utility of Tumour Mutational Signatures for Identifying Hereditary Colorectal Cancer and Polyposis syndromes
Familial Aspects of Cancer Research and Practice (Kingscliff, Australia) (2019). Accepted oral presentation. - Evaluating the clinical applicability of somatic mutational signatures
University of Melbourne Cancer Center Research (UMCCR) (2018). Seminar. - Identifying and characterising high resolution mutational signatures from DNA mismatch repair deficient tumours
Australian Bioinformatics and Computational Biology Society (Melbourne, Australia) (2018). Accepted oral presentation.
Funding
- Cancer Council Grants-in-aid (2025-2027) - $359,850
Preventing bowel cancer caused by gut bacteria - NHMRC Investigator Grant (2024-2028) - $662,040
Clinical application of tumour mutational signatures for precision prevention of colorectal cancer - Cure Cancer Research Grant (2024) - $100,000
Genomic profiling of non-cancerous bowel tumours to improve prediction of progression to bowel cancer - The University of Melbourne - Travel Funding (2024) - $4,646
Early Career Academic Conference Support Scheme - Cancer Council Victoria Research Grant (2023) - $81,030
Linking gut bacteria to the development of colorectal cancer using multi-omic profiling
Supervision
- Elizabeth (Yen Lin) Chu (2023 onwards)
PhD student, The University of Melbourne. co-supervised with A/Prof Dan Buchanan and Dr Eric Joo - Daniel Vo (2023)
Medical student, The University of Melbourne. Co-supervised with A/Prof Dan Buchanan
Teaching
- Guest Lecturer (Semester 1, 2019):
Diagnostic Genomics at Melbourne Dental School, The University of Melbourne - Tutor (Semester 1, 2019):
Master of Business Analytics at The University of Melbourne (54 students) - Instructor (October, 2018; June, 2018; March, 2018; September, 2017):
Introduction to Unix at Melbourne Bioinformatics (68 students) - Instructor (June, 2018; March, 2018):
Introduction to High Performance Computing at Melbourne Bioinformatics (21 students) - Subject Co-ordinator (Semester 2, 2017):
Algorithms for Functional Genomics at The University of Melbourne (44 students) - Guest lecturer (Semester 1, 2017):
Master of Business Analytics at The University of Melbourne (45 students)
Projects
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